Why the study?
Does perioperative administration of dexmedetomidine reduce the incidence of postoperative acute kidney injury in adult patients undergoing cardiac surgery?
Does perioperative administration of dexmedetomidine reduce the incidence of postoperative acute kidney injury in adult patients undergoing cardiac surgery?
Perioperative dexmedetomidine may reduce the incidence of postoperative acute kidney injury in adults undergoing cardiac surgery.
May support dexmedetomidine to reduce AKI after cardiac surgery; extends Level 1 meta-analytic evidence from RCTs.
Perioperative administration of dexmedetomidine in adult patients undergoing cardiac surgery may reduce the incidence of postoperative AKI. Future trials are needed to determine the dose and timing of dexmedetomidine in improving outcomes, especially in patients with decreased baseline kidney function.
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Liu et al. (2018) studied this question.
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