Does intensive lipid-lowering therapy improve regression of coronary lesions and reduce cardiovascular events in men with coronary artery disease and high levels of apolipoprotein B?
Intensive lipid-lowering therapy promotes regression of coronary lesions and reduces cardiovascular events in high-risk men with coronary artery disease and high apolipoprotein B.
In men with coronary artery disease who were at high risk for cardiovascular events, intensive lipid-lowering therapy reduced the frequency of progression of coronary lesions, increased the frequency of regression, and reduced the incidence of cardiovascular events.
Brown et al. (1990) studied this question.