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Shows regional citrate anticoagulation improves efficacy and reduces adverse effects compared to systemic heparin in intensive care, indicating its preference for continuous renal replacement therapy.
RCA per se is safe and effective for anticoagulation of CRRT. Compared to SHA, efficacy of anticoagulation is improved and adverse effects are reduced. RCA can be recommended as the anticoagulation mode of choice for CRRT in most ICU patients.
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Kindgen‐Milles et al. (2018) studied this question.
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