Does quercetin prevent EV71-induced cell injury and inhibit viral replication in host cells?
Quercetin demonstrates potential as an antiviral agent against Enterovirus 71 by inhibiting its 3C protease and blocking viral replication in vitro.
Quercetin can effectively prevent EV71-induced cell injury with low toxicity to host cells. Quercetin may act in more than one way to deter viral infection, exhibiting some preventive and a powerful therapeutic effect against EV71. Further, quercetin potently inhibits EV71 3Cpro activity, thereby blocking EV71 replication.
Yao et al. (Tue,) studied this question.
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