Validation study demonstrates high accuracy of quantitative lutetium-177 SPECT/CT in phantom and clinical settings, suggesting improved dosimetry and therapy monitoring.
QSPECT has high accuracy both in our phantom model and in clinical practice following [(177)Lu]octreotate therapy. This has the potential to yield more accurate dosimetry estimates than planar imaging and facilitate therapeutic response assessment. Validating this method with other radionuclides could open the way for many other research and clinical applications.
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Beauregard et al. (2011) studied this question.
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