What question did this study set out to answer?

Identify a specific gene panel to enable sensitive and specific monitoring of minimal residual disease in pediatric acute myeloid leukemia.

April 15, 2006Clinical Cancer ResearchOpen Access

Identification of a Set of Seven Genes for the Monitoring of Minimal Residual Disease in Pediatric Acute Myeloid Leukemia

View Full Paper

Ask AI

Bookmark

Authors

DSDaniel SteinbachUniversität Ulm ASAlexander SchrammKlinik und Poliklinik für Kinder- und Jugendmedizin AEAngelika EggertCharité - Universitätsmedizin Berlin

Discussion

Member takes

Implication

Biomarker study reveals a seven-gene panel for monitoring minimal residual disease in pediatric acute myeloid leukemia, suggesting potential therapeutic targets for immunotherapy.

Key Points

Identify a specific gene panel to enable sensitive and specific monitoring of minimal residual disease in pediatric acute myeloid leukemia.
Evaluated gene expression signatures to select candidate biomarkers for tracking minimal residual disease (MRD) in pediatric acute myeloid leukemia (AML).
Identified a panel of seven distinct genes capable of providing sensitive and specific surveillance of MRD in AML.
Identified markers within the panel, including MSLN, that have direct relevance to leukemogenesis and represent viable targets for immunotherapy.

Cite This Study

Steinbach et al. (2006) studied this question.

synapsesocial.com/papers/69dbef7840b636d1dda3c5dd https://doi.org/10.1158/1078-0432.ccr-05-2552

View Full Paper

Ask AI

Bookmark

Implication

Biomarker study reveals a seven-gene panel for monitoring minimal residual disease in pediatric acute myeloid leukemia, suggesting potential therapeutic targets for immunotherapy.

Identification of a Set of Seven Genes for the Monitoring of Minimal Residual Disease in Pediatric Acute Myeloid Leukemia

Discussion

Member takes

Implication

Key Points

Cite This Study

Identification of a Set of Seven Genes for the Monitoring of Minimal Residual Disease in Pediatric Acute Myeloid Leukemia

Discussion

Member takes

Implication

Key Points

Cite This Study

Also Consider

Also Consider