Our ex vivo phantom study indicates that DECT with the use of a dedicated, iron-specific 3-material decomposition algorithm allows for the accurate quantification of LFC, even in the presence of iron and iodinated CM. VNI images reconstructed from DECT data equal nonenhanced SECT data of liver without CM by eliminating iron and iodine from the images. No added value was seen for DECT as compared with SECT for quantification of LFC in the absence of iron and iodine.
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Fischer et al. (2011) studied this question.
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