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March 9, 2023Circulation Research59 citationsOpen Access

Platelet-Derived MicroRNAs Regulate Cardiac Remodeling After Myocardial Ischemia

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JSJan Philipp SchütteMMMailin-Christin MankeKHKatherina Hemmen

Structured PICO

Do platelet-derived miRNAs regulate cardiac remodeling and inflammation after myocardial ischemia/reperfusion?

P
Population
Myocardial ischemia/reperfusion (I/R) model
I
Intervention
Platelet-derived miRNA
O
Outcome
Myocardial inflammation and structural remodelingsurrogate

Platelet-derived miRNAs are critically involved in regulating myocardial inflammation and structural remodeling after ischemia/reperfusion injury.

Abstract

The present study discloses a critical role of platelet-derived miRNA in myocardial inflammation and structural remodeling processes following myocardial I/R.

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Schütte et al. (2023) studied this question.

synapsesocial.com/papers/69dc0cd70648942b0a9c7ce6https://doi.org/10.1161/circresaha.122.322459
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