The missing continuity of the connective tissue net in the muscularis propria seems to abolish coordinated alternative movement of circular and longitudinal muscles. Therefore, the lack of coordinated propulsive activity of the colon results in a therapy-resistant chronic constipation, with a hypoperistalsis syndrome.
No takes yet. Share an insight, caveat, or question.
W. Meier‐Ruge (1998) studied this question.