Why the study?
Does indobufen improve graft patency compared to aspirin and dipyridamole in patients after coronary artery bypass surgery?
Does indobufen improve graft patency compared to aspirin and dipyridamole in patients after coronary artery bypass surgery?
Indobufen is equally effective as the combination of aspirin and dipyridamole in preventing graft occlusion after coronary artery bypass surgery.
Indobufen offers a viable alternative to aspirin-dipyridamole for post-CABG graft protection; confirms equivalence in meta-analysis.
Two multicentre CABG studies performed in different countries in patients with similar characteristics showed similar results in terms of graft patency. On the basis of the combined analysis, the two treatments can reasonably be considered to be equally effective in the prevention of graft occlusion.
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Cataldo et al. (1998) studied this question.