Why the study?
Does the increasing use of reperfusion strategies and adjunct medical therapy reduce the incidence and hospital mortality of cardiac rupture in patients with acute ST-elevation myocardial infarction?
Population
425 patients with acute ST-elevation myocardial infarction and cardiac rupture
Comparison
Reperfusion strategies and adjunct medical therapy vs Historical practice
Design
Cohort
Follow-up
hospital stay
Authors
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Supports reperfusion strategies in STEMI; leaves open causal effects on rupture from observational data.
Does the increasing use of reperfusion strategies and adjunct medical therapy reduce the incidence and hospital mortality of cardiac rupture in patients with acute ST-elevation myocardial infarction?
The incidence and hospital mortality of cardiac rupture complicating STEMI have declined over a 30-year period, likely driven by advances in reperfusion and medical therapies.
Figueras et al. (2008) studied this question.
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