Literature review reveals the complex causes of tendinopathy, suggesting advanced treatment strategies.
Conclusions: The heterogeneity of the clinical and histological presentation confirms the multifactorial nature of tendinopathy and explains the therapeutic challenges and frequent treatment failures. The authors suggest that integrating knowledge regarding mechanotransduction, inflammation, metabolism, and the role of intratendinous pressure may provide a basis for developing more precise and effective treatment strategies for tendinopathy.
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Grabowski et al. (2026) studied this question.
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