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April 13, 2026Transfusion0 citations

Utilization and safety outcomes following the use of low titer group O whole blood in non‐trauma patients

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JBJozsef BordasEFErin FeeneyCLChristine Leeper

Key Points

  • This research aims to evaluate the utilization and safety of low titer group O whole blood (LTOWB) in non-trauma patients.
  • Analyzed the use of LTOWB in non-trauma adult populations
  • Focused on patients with gastrointestinal and cardiovascular bleeding
  • Compared LTOWB to traditional component therapy in terms of safety outcomes
  • LTOWB was frequently used for managing gastrointestinal and cardiovascular bleeding
  • LTOWB demonstrated safety as an alternative to component therapy
  • Further studies are needed to assess efficacy and clinical outcomes in severe hemorrhage cases

Abstract

In non-trauma settings, LTOWB was most commonly utilized in patients with gastrointestinal and cardiovascular bleeding. LTOWB is a safe alternative to component therapy in non-trauma adult populations. However, additional studies are needed to focus on efficacy and clinical outcomes in non-trauma patients that receive LTOWB for severe hemorrhage.

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Cite This Study

Bordas et al. (2026) studied this question.

synapsesocial.com/papers/69dc887f3afacbeac03ea559https://doi.org/10.1111/trf.70172
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