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April 13, 2026Journal of Neuro-OncologyOpen Access

Neurobehavioral outcomes and associated risk factors in pediatric brain tumor survivors

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Authors

YWYuliang WangWCWing Lam ChanFLFei Li

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Overview

This cohort study investigates neurobehavioral challenges in pediatric brain tumor survivors, suggesting sleep improvement for better outcomes.

Key Points

  • The study aims to evaluate long-term neurobehavioral outcomes and identify associated risk factors in pediatric brain tumor survivors.
  • Retrospective cohort design involving 274 pediatric brain tumor survivors
  • Cross-sectional follow-up survey completed by 107 survivors
  • Assessment of emotional/behavioral difficulties, sleep variables, and quality of life compared with community cohorts
  • 10.6% of survivors had ADHD and 6.9% had ASD, higher than the general population
  • Survivors exhibited more emotional/behavioral symptoms and poorer quality of life
  • Factors like younger diagnosis age, seizure history, and supratentorial tumors correlated with increased difficulties
  • Better sleep quality associated with fewer ADHD symptoms and emotional problems

Cite This Study

Wang et al. (2026) studied this question.

synapsesocial.com/papers/69dc89473afacbeac03eb0f3https://doi.org/10.1007/s11060-026-05558-8
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