Why the study?
Does bladder preservation lead to retaining bladder function in patients with nonmetastatic bladder/prostate rhabdomyosarcoma?
Does bladder preservation lead to retaining bladder function in patients with nonmetastatic bladder/prostate rhabdomyosarcoma?
Bladder preservation strategies in nonmetastatic bladder/prostate rhabdomyosarcoma result in 40% of all patients surviving event-free with normal bladder function at 6 years.
May support bladder preservation consideration; leaves open need for prospective trials to confirm outcomes.
Of patients with nonmetastatic BP RMS on IRS IV 82% survived 6 years. Bladder function was preserved in 55% (36/66) of event-free survivors. Of all patients entered on study 40% (36 of 88) survive event-free with apparently normal functioning bladders. More precise long-term evaluation of bladder and sexual function will require application of better tools such as urodynamic studies and validated patient surveys.
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Arndt et al. (2004) studied this question.
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