May 3, 2004The Journal of Urology133 citations

Does Bladder Preservation (As a Surgical Principle) Lead to Retaining Bladder Function in Bladder/Prostate Rhabdomyosarcoma? Results From Intergroup Rhabdomyosarcoma Study Iv

CACarola ArndtMayo Clinic DRDavid A. RodebergUniversity of Kentucky PBPhilip P. BreitfeldAmerican Institute of Certified Public Accountants

Structured PICO

Does bladder preservation lead to retaining bladder function in patients with nonmetastatic bladder/prostate rhabdomyosarcoma?

Population

Patients with nonmetastatic bladder/prostate rhabdomyosarcoma (BP RMS) enrolled in the Intergroup Rhabdomyosarcoma Study IV (n=88)

Intervention

Bladder preservation (as a surgical principle)

Outcome

6-year survival and preservation of bladder functionhard clinical

Bladder preservation strategies in nonmetastatic bladder/prostate rhabdomyosarcoma result in 40% of all patients surviving event-free with normal bladder function at 6 years.

Abstract

Of patients with nonmetastatic BP RMS on IRS IV 82% survived 6 years. Bladder function was preserved in 55% (36/66) of event-free survivors. Of all patients entered on study 40% (36 of 88) survive event-free with apparently normal functioning bladders. More precise long-term evaluation of bladder and sexual function will require application of better tools such as urodynamic studies and validated patient surveys.

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