Why the study?
Does ultrasound speckle tracking imaging detect changes in right ventricular systolic function in patients with patent ductus arteriosus compared to healthy controls?
Does ultrasound speckle tracking imaging detect changes in right ventricular systolic function in patients with patent ductus arteriosus compared to healthy controls?
Speckle tracking imaging demonstrates that right ventricular systolic function is decreased in patients with patent ductus arteriosus, with further impairment in those who develop pulmonary arterial hypertension.
Speckle tracking may identify subclinical RV impairment in PDA; hypothesis-generating and requires prospective validation before clinical adoption.
Objective To assess right ventricular systolic function in patients with patent ductus arteriosus (PDA) by speckle tracking imaging (STI). Methods Right ventricular peak systolic global and segmental strain (S), strain rate (SR) were measured respectively in 35 patients with patent ductus arteriosus and 37 healthy controls by STI from the apical four-chamber view, and compared the indexes above among the three groups: the pure PDA group, the PAH group (the PDA patients with pulmonary arterial hypertension), and the controls group. Results Right ventricular peak systolic strain (S) of basal, mid, apical segment in free wall and the global S were lower in PDA group than the controls group (p<0.01), while higher than the PAH group (p<0.01); S and SR were significantly lower in PAH group than the controls group (p<0.01). Conclusions STI may be used to objectively evaluate the right ventricular systolic function in patients with PDA. Right ventricular systolic function is decreased in patients of PDA without PAH, and significantly decreased in the patients with PAH.
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Guodong Han (2011) studied this question.