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October 12, 2020International Journal of Gynecological CancerOpen Access

PORTEC-4a: international randomized trial of molecular profile-based adjuvant treatment for women with high-intermediate risk endometrial cancer

Anne Sophie V M van den Heerik Nanda Horeweg Remi A. Nout Ludy Lutgens Elzbieta M. van der Steen‐Banasik Henrike Westerveld Hetty A. van den Berg Annerie Slot Friederike Koppe Stefan Kommoss Jan Willem Mens Marlies E. Nowee S. Bijmolt David Cibula Tanja C. Stam Ina M. Jürgenliemk‐Schulz An Snyers Moritz Hamann A.G. Zwanenburg V. Coen Katrien Vandecasteele Charles Gillham Cyrus Chargari Karen Verhoeven-Adema Hein Putter Wilbert B. van den Hout Bastiaan G. Wortman Hans W. Nijman Tjalling Bosse Carien L. Creutzberg

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Abstract

The trial is registered at clinicaltrials.gov (NCT03469674) and ISRCTN (11659025).

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Cite This Study

Heerik et al. (2020) studied this question.

synapsesocial.com/papers/69dcc94cf3d3790cb7133d57 https://doi.org/10.1136/ijgc-2020-001929

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Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

1Ten-year results of the PORTEC-2 trial for high-intermediate risk endometrial carcinoma: improving patient selection for adjuvant therapyRCT · 2018 · 286 citations
2Integrated genomic characterization of endometrial carcinomaOriginal Research · 2013 · 5,766 citations
3A clinically applicable molecular-based classification for endometrial cancersRetrospective Study · 2015 · 978 citations
4Improved Risk Assessment by Integrating Molecular and Clinicopathological Factors in Early-stage Endometrial Cancer—Combined Analysis of the PORTEC CohortsPrognostic Study · 2016 · 848 citations
5L1CAM further stratifies endometrial carcinoma patients with no specific molecular risk profilePrognostic Study · 2018 · 143 citations

More related papers

Molecular-integrated risk profile to determine adjuvant radiotherapy in endometrial cancer: Evaluation of the pilot phase of the PORTEC-4a trial2018
Clinicopathological and molecular characterisation of ‘multiple‐classifier’ endometrial carcinomas2019

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