Radiomic analysis of the deltoid and scapula: identification of computed tomography-image based measurements predictive of pain, motion, and function before and after shoulder arthroplasty

This analysis of >4,000 preoperative CT scans identified numerous radiomic features of the deltoid and scapula that were highly predictive of pain, motion, and function before and after aTSA/rTSA. These most predictive radiomic features were aggregated into unique morphological clusters of deltoids and scapula that were associated with differences in clinical outcomes before and after aTSA/rTSA. Shape-based radiomic features were more predictive than first-order and second-order radiomic features, suggesting that these more interpretable measurements are more clinically relevant and could be more readily incorporated into future radiomic-based clinical decision support tools. Future work is required to further validate these radiomic findings and refine the proposed clustering analysis.