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May 6, 2021NeurosurgeryOpen Access

Genome-Wide Association Study Identifies Genetic Risk Factors for Spastic Cerebral Palsy

Andrew T. Hale Oluwatoyin Akinnusotu Jing He Janey Wang Natalie Hibshman Chevis N. Shannon Robert P. Naftel

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Abstract

To our knowledge, we perform the first GWAS of spastic CP. Our study indicates that genetic variation contributes to CP risk.

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Cite This Study

Hale et al. (2021) studied this question.

synapsesocial.com/papers/69dcd194e3a90a2e2f1332c0 https://doi.org/10.1093/neuros/nyab184

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Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

1Antecedents of Cerebral PalsyOriginal Research · 1986 · 941 citations
2Cerebral Palsy—Trends in Epidemiology and Recent Development in Prenatal Mechanisms of Disease, Treatment, and PreventionReview · 2017 · 371 citations
3Genetic insights into the causes and classification of the cerebral palsiesOriginal Research · 2012 · 172 citations
4Genome-wide mega-analysis identifies 16 loci and highlights diverse biological mechanisms in the common epilepsiesCase-Control Study · 2018 · 482 citations
5Identification of common genetic risk variants for autism spectrum disorderCase-Control Study · 2019 · 2,403 citations

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