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July 1, 2011Archives of General PsychiatryOpen Access

Downregulated Kynurenine 3-Monooxygenase Gene Expression and Enzyme Activity in Schizophrenia and Genetic Association With Schizophrenia Endophenotypes

Ikwunga Wonodi O. Colin Stine Korrapati V. Sathyasaikumar Rosalinda C. Roberts Braxton D. Mitchell L. Elliot Hong Yasushi Kajii Gunvant K. Thaker Robert Schwarcz

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Abstract

Our results provide converging lines of evidence implicating reduced KMO activity in the etiopathophysiology of schizophrenia and related neurocognitive deficits.

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Wonodi et al. (2011) studied this question.

synapsesocial.com/papers/69dcd1e0854f360ad6359316 https://doi.org/10.1001/archgenpsychiatry.2011.71

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