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June 27, 2020Genes Chromosomes and CancerOpen Access

Frequency and prognostic impact of PAX5 p.P80R in pediatric acute lymphoblastic leukemia patients treated on an AIEOP‐BFM acute lymphoblastic leukemia protocol

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MJMareike JungMedizinische Hochschule Hannover MSMaximilian SchieckMedizinische Hochschule Hannover WHWinfried HofmannMedizinische Hochschule Hannover

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Jung et al. (2020) studied this question.

synapsesocial.com/papers/69dd1ce7aa9a964e8d133601 https://doi.org/10.1002/gcc.22882

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Also Consider

Synapse has enriched 3 closely related papers on similar clinical questions. Consider them for comparative context:

1Molecular response to treatment redefines all prognostic factors in children and adolescents with B-cell precursor acute lymphoblastic leukemia: results in 3184 patients of the AIEOP-BFM ALL 2000 study2010 · 794 citations
2Transcriptional landscape of B cell precursor acute lymphoblastic leukemia based on an international study of 1,223 cases2018 · 329 citations
3Intragenic amplification of PAX5: a novel subgroup in B-cell precursor acute lymphoblastic leukemia?2017 · 38 citations