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April 1, 2018RMD OpenOpen Access

Predictive value of serum calprotectin (S100A8/A9) for clinical response after starting or tapering anti-TNF treatment in patients with rheumatoid arthritis

Lieke Tweehuysen Nathan den Broeder Noortje van Herwaarden Leo A. B. Joosten P.L. van Lent Thomas Vogl F.H.J. van den Hoogen Rogier M. Thurlings Alfons A den Broeder

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Abstract

NTR4647 (BIO-TOP study) and NTR3216 (DRESS study); Pre-results.

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Tweehuysen et al. (2018) studied this question.

synapsesocial.com/papers/69dd1d067a14526fc01334c1 https://doi.org/10.1136/rmdopen-2018-000654

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Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

1Direct comparison of treatment responses, remission rates, and drug adherence in patients with rheumatoid arthritis treated with adalimumab, etanercept, or infliximab: Results from eight years of surveillance of clinical practice in the nationwide Danish DANBIO registryPrognostic Study · 2009 · 538 citations
2The relationship between disease activity and radiologic progression in patients with rheumatoid arthritis: A longitudinal analysisRCT · 2004 · 271 citations
3MRP-8 and MRP-14, two abundant Ca2+-binding proteins of neutrophils and monocytesReview · 1993 · 395 citations
4Purification and Partial Characterization of a Highly Immunogenic Human Leukocyte Protein, the L1 AntigenOriginal Research · 1983 · 227 citations
5Calprotectin as a Biomarker for Rheumatoid Arthritis: A Systematic ReviewPrognostic Study · 2015 · 100 citations

Calprotectin (S100A8/A9) and S100A12 are associated with measures of disease activity in a longitudinal study of patients with rheumatoid arthritis treated with infliximab2016
Serum Calprotectin Versus Acute‐Phase Reactants in the Discrimination of Inflammatory Disease Activity in Rheumatoid Arthritis Patients Receiving Tumor Necrosis Factor Inhibitors2015
Myeloid-related Protein 8/14 Levels in Rheumatoid Arthritis: Marker of Disease Activity and Response to Methotrexate2016
Study on the implementation of the 2015 EULAR/ACR recommendations for polymyalgia rheumatica in clinical practiceRMD Open · 2026
Early features of cellular ageing impair differentiation capacity in human lymph node fibroblasts prior to rheumatoid arthritis onsetRMD Open · 2026

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