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July 20, 2011New England Journal of MedicineOpen Access

Carotid-Wall Intima–Media Thickness and Cardiovascular Events

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Why the study?

Does carotid-wall intima-media thickness measurement improve the classification of risk of cardiovascular disease in the Framingham Offspring Study cohort?

Population

Framingham Offspring Study cohort

Design

Cohort

Authors

JPJoseph F. PolakBoston University
Michael Pencina
Michael PencinaGeneral / Preventive / Lipids
KPKarol M. PencinaBrigham and Women's Hospital

Discussion

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Implication

Modest internal carotid IMT and plaque gains in CVD risk classification warrant no practice change; leaves validation in prospective trials open.

Structured PICO

Does carotid-wall intima-media thickness measurement improve the classification of risk of cardiovascular disease in the Framingham Offspring Study cohort?

P
Population
Framingham Offspring Study cohort
I
Intervention
Measurement of maximum internal and mean common carotid-artery intima-media thickness and presence of plaque
O
Outcome
Cardiovascular outcomes and classification of risk of cardiovascular diseasehard clinical

Maximum internal carotid artery intima-media thickness and plaque presence modestly improve cardiovascular risk classification.

Cite This Study

Polak et al. (2011) studied this question.

synapsesocial.com/papers/69dd358b7808b00a4799b709https://doi.org/10.1056/nejmoa1012592

Topics

Women and heart disease
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