Carotid plaque, a subclinical precursor of vascular events
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Discussion
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Implication
May support risk stratification in multiethnic cohorts; leaves open surrogate endpoint role pending randomized validation.
Key Points
- To evaluate maximum carotid plaque thickness as a noninvasive marker of subclinical atherosclerosis and assess its relationship with future vascular outcomes.
- Assessed maximum carotid plaque thickness as a noninvasive surrogate endpoint in a multiethnic cohort.
- Maximum carotid plaque thickness is associated with an elevated risk of subsequent vascular events in a multiethnic cohort.
- The measurement provides a simple, inexpensive tool suitable for vascular risk stratification in preventive interventions and clinical trials.
Cite This Study
Rundek et al. (2008) studied this question.