Key result
Invasive strategy reduces composite events vs conservative management in patients aged ≥80 with NSTE-ACS.
Why the study?
Does an invasive strategy improve event-free survival and reduce composite events compared to a conservative strategy in patients aged ≥80 years with NSTE-ACS?
Does an invasive strategy improve event-free survival and reduce composite events compared to a conservative strategy in patients aged ≥80 years with NSTE-ACS?
In older patients (≥80 years) presenting with NSTE-ACS, an invasive management strategy provides superior long-term event-free survival compared to a conservative approach.
Favors invasive over conservative strategy for NSTE-ACS in patients ≥80 years; extends RCT evidence to octogenarians.
In patients aged ≥80 years with NSTE-ACS, the invasive strategy was superior to the conservative strategy in the reduction of composite events and demonstrated a significant gain in event-free survival. (The After Eighty Study: a randomized controlled trial; NCT01255540).
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Berg et al. (2023) studied this question. An invasive strategy was superior to a conservative strategy for reducing composite events and improving event-free survival in patients aged ≥80 years with NSTE-ACS.
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