Why the study?
Is vascular risk associated with prospective cognitive decline in clinically normal elderly individuals?
Is vascular risk associated with prospective cognitive decline in clinically normal elderly individuals?
Vascular risk factors, alone and synergistically with beta-amyloid burden, are associated with prospective cognitive decline in clinically normal older adults.
May warrant vascular monitoring in normal elderly; hypothesis-generating for Aβ synergy on decline.
In this study, vascular risk was associated with prospective cognitive decline in clinically normal older adults, both alone and synergistically with Aβ burden. Vascular risk may complement imaging biomarkers in assessing risk of prospective cognitive decline in preclinical Alzheimer disease.
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Rabin et al. (2018) studied this question.
Synapse has enriched 3 closely related papers on similar clinical questions. Consider them for comparative context: