Why the study?
How do hip geometry, strength, and estimated fracture risk compare between women with anorexia nervosa and overweight/obese women?
How do hip geometry, strength, and estimated fracture risk compare between women with anorexia nervosa and overweight/obese women?
Variability in soft tissue padding, captured by attenuated factor of risk, may help explain site-specific fracture risk not captured by BMD alone in women with anorexia nervosa versus obesity.
May refine hip fracture risk assessment beyond BMD in anorexia and obesity; leaves open prospective validation of factor of risk.
Femoral geometry by HSA, hip BMD, and factor of risk for hip fracture attenuated by soft tissue are impaired in AN and superior in obesity, suggesting higher and lower hip fracture risk, respectively. Only attenuated factor of risk was associated with fragility fracture prevalence, suggesting that variability in soft tissue padding may help explain site-specific fracture risk not captured by BMD.
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Bachmann et al. (2014) studied this question.
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