The predominance of genotype P[4]G2 rotavirus in a highly vaccinated population suggests the vaccine may be less protective against this specific strain.
We identified 21 rotaviruses in 129 patients with diarrhea in a Brazilian city with high rotavirus vaccine coverage. All rotaviruses were genotype P4G2 with 1 mixed infection with PNTG9. Although virus predominance could have occurred randomly, the vaccine may be less protective against P4G2. Prospective surveillance is urgently needed.
Gurgel et al. (Mon,) studied this question.
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