A novel pyrene-conjugated squaraine fluorescent probe SQ-P, which could self-assemble into nanoparticles in aqueous solution through multiple interactions, was designed to selectively detect serum albumin with a turn-on response in the near infrared (NIR) region. More importantly, the probe can quantitatively detect serum albumin in human sera, and be used for imaging in living cells.
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Fan et al. (2015) studied this question.
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