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March 30, 2019SHILAP Revista de lepidopterologíaOpen Access

Long noncoding RNA Pvt1 regulates the immunosuppression activity of granulocytic myeloid-derived suppressor cells in tumor-bearing mice

Yu Zheng Xinyu Tian Tingting Wang Xueli Xia Fenghua Cao Jie Tian Ping Xu Jie Ma Huaxi Xu Shengjun Wang

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Abstract

Taken together, our results demonstrate a critical role for lncRNA Pvt1 in regulating the immunosuppression activity of G-MDSCs, and lncRNA Pvt1 might thus be a potential antitumor immunotherapy target.

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Cite This Study

Zheng et al. (2019) studied this question.

synapsesocial.com/papers/69dd4e4d0644c7b49d40ccb4 https://doi.org/10.1186/s12943-019-0978-2

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Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

1Long Non-Coding RNA HOXA Transcript Antisense RNA Myeloid-Specific 1–HOXA1 Axis Downregulates the Immunosuppressive Activity of Myeloid-Derived Suppressor Cells in Lung CancerOriginal Research · 2018 · 111 citations
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4Subsets of Myeloid-Derived Suppressor Cells in Tumor-Bearing MiceIn Vitro Study · 2008 · 1,645 citations
5Recommendations for myeloid-derived suppressor cell nomenclature and characterization standardsOriginal Research · 2016 · 2,740 citations

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