Key result
Opioid-free anaesthesia improves 24-hour quality of recovery compared to opioid-based anaesthesia.
Why the study?
There is ongoing debate about whether opioid-free anaesthesia improves patient-reported quality of recovery after general anaesthesia.
Does opioid-free anaesthesia improve quality of recovery in adult patients undergoing general anaesthesia?
Population
Adult patients undergoing general anaesthesia
Comparison
Opioid-free anaesthesia vs opioid-based anaesthesia
Design
Systematic review and meta-analysis of randomized controlled trials
Follow-up
24 hours postoperatively
Authors
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Opioid-free anaesthesia may improve patient-reported quality of recovery at 24 hours postoperatively compared to opioid-based anaesthesia, though evidence is limited by heterogeneity.
Meta-Analysis
Does opioid-free anaesthesia improve quality of recovery in adult patients undergoing general anaesthesia?
Opioid-free anaesthesia may improve patient-reported quality of recovery at 24 hours postoperatively compared to opioid-based anaesthesia, though evidence is limited by heterogeneity.
Liu et al. (2024) conducted a meta-analysis in Patients undergoing general anaesthesia. Opioid-free anaesthesia (OFA) vs. Opioid-based anaesthesia (OBA) was evaluated on Quality of recovery measured with the QoR scale. Opioid-free anaesthesia improved the quality of recovery at postoperative 24 hours compared to opioid-based anaesthesia, despite significant heterogeneity (91%).
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