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February 5, 2008GutOpen Access

Increased capsaicin receptor TRPV1-expressing sensory fibres in irritable bowel syndrome and their correlation with abdominal pain

Ayesha Akbar Y. Yiangou P. Facer Julian R.F. Walters P Anand Subrata Ghosh

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Abstract

Increased TRPV1 nerve fibres are observed in IBS, together with a low-grade inflammatory response. The increased TRPV1 nerve fibres may contribute to visceral hypersensitivity and pain in IBS, and provide a novel therapeutic target.

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Akbar et al. (2008) studied this question.

synapsesocial.com/papers/69dd500c656f15f1fc10109a https://doi.org/10.1136/gut.2007.138982

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