Why the study?
Does the withdrawal of approximately 450 ml blood reduce VO2peak, time to exhaustion, and alter phase II VO2 kinetics in healthy subjects?
Population
11 healthy subjects (mean age 23 +/- 6 years, body mass 77.2 +/- 11.0 kg)
Comparison
Voluntary donation of approximately 450 ml blood vs Control condition (before blood donation)
Design
Other
Follow-up
24 h following blood donation
Authors
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Blood donation may impair exercise capacity in healthy adults; leaves open effects on VO2 kinetics in clinical populations.
Does the withdrawal of approximately 450 ml blood reduce VO2peak, time to exhaustion, and alter phase II VO2 kinetics in healthy subjects?
A standard blood donation of 450 ml significantly reduces VO2peak and exercise tolerance but does not affect fundamental phase VO2 on-kinetics during severe-intensity exercise.
Burnley et al. (2006) studied this question.
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