Clonal Evolution of PPM1D Mutations in the Spectrum of Myeloid Disorders

David Fandrei; Jean Pegliasco; Florence Pasquier; Nathalie Ibrahim; Maria Kfoury; Céline Berthon; Maël Heiblig; Delphine Lebon; Ambroise Marçais; Mathieu Meunier; Ahmad Al Jijakli; Émilie Lemasle; Sylvain Chantepie; Cécile Pautas; Pierre‐Yves Dumas; Célia Salanoubat; Diana Carp; Romain Loyaux; Cyril Quivoron; Arnaud Pagès; Bastien Job; Remy Jelin; Gérôme Jules-Clément; Iléana Antony‐Debré; Aline Renneville; Sophie Cotteret; Raphaël Itzykson; Hervé Dombret; Nicolas Duployez; Nathalie Droin; Alexandra Léary; Christophe Marzac; Elsa Bernard; Jean‐Baptiste Micol

doi:10.1158/1078-0432.ccr-24-3683

Abstract

PPM1D mutations found in clonal hematopoiesis can spontaneously regress after treatment discontinuation; however, they can also be found in the dominant clone in AML/MDS.

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Fandrei et al. (2025) studied this question.

synapsesocial.com/papers/69dd59534917c2595e100f83 https://doi.org/10.1158/1078-0432.ccr-24-3683

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Clonal Evolution of PPM1D Mutations in the Spectrum of Myeloid Disorders

Abstract

Discussion

Cite This Study

Clonal Evolution of PPM1D Mutations in the Spectrum of Myeloid Disorders

Abstract

Discussion

Cite This Study

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