Formation, structure and properties of biocompatible TiZrHfNbTa high-entropy alloys

Biocompatibility of HEAs in the TiZrHfNbTa system in which all the constituents are non-toxic and allergy-free was scrutinized systematically, and novel biomechanical materials with a unique combination of low modulus (57 GPa, almost half that of conventional biomedical titanium alloys), good mechanical biocompatibility and low magnetic susceptibility (1.71 × 10−6 cm3 g−1, similar to that of pure Zr) were successfully developed. Moreover, the underlying mechanisms responsible for phase formation and promising properties were explored. This work not only offers a series of novel bio-metallic materials with prominent properties for practical applications, but also shed light on understanding of phase formation and strengthening of HEAs in general.