School survey finds reduced rapid diagnostic test sensitivity at low antigen levels in schoolchildren, highlighting the need for high-sensitivity assays in malaria elimination.
RDTs remain a useful surveillance tool, particularly in moderate- to high-transmission settings. However, reduced sensitivity at lower antigen concentrations in hypo-endemic areas highlights the value of complementary high-sensitivity assays for elimination-focused strategies. Future research should explore the application of these integrated diagnostic approaches in regions without seasonal malaria chemoprophylaxis intervention.
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Diallo et al. (2025) studied this question.
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