April 16, 2025Open Access

ADAR1-high tumor-associated macrophages induce drug resistance and are therapeutic targets in colorectal cancer

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Abstract

This study revealed that ADAR1-high TAMs are crucial in regulating drug resistance in CRC and that targeting ADAR1 in TAMs could be a promising treatment approach for overcoming drug resistance in CRC.

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Umeda et al. (Wed,) studied this question.

synapsesocial.com/papers/69dd5d654917c2595e101450 https://doi.org/https://doi.org/10.1186/s12943-025-02312-y

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