Population
Chick chorioallantoic membrane (CAM) in vivo model of angiogenesis (chick embryo development days 8-13)
Design
Preclinical
Follow-up
13 days
Authors
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Suggests NO inhibits angiogenesis in CAM model; leaves open human relevance and therapeutic targeting.
In the chick chorioallantoic membrane model, endogenous NO production parallels angiogenesis progression and acts as an endogenous inhibitor of the process.
Pipili‐Synetos et al. (2000) studied this question.
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