Answers are grounded in this paper and cite their sources.
Our data show that myelin modulates the phenotype of macrophages by PPAR activation, which may subsequently dampen MS lesion progression. Moreover, our results suggest that myelin-derived PS mediates PPARβ/δ activation in macrophages after myelin uptake. The immunoregulatory impact of naturally-occurring myelin lipids may hold promise for future MS therapeutics.
No takes yet. Share an insight, caveat, or question.
Bogie et al. (2013) studied this question.
Synapse has enriched 10 related papers. Consider them for comparative context: