Why the study?
Does adherence to antihypertensive agents reduce cardiovascular outcomes in patients after an ischemic stroke?
Does adherence to antihypertensive agents reduce cardiovascular outcomes in patients after an ischemic stroke?
Adherence to antihypertensive therapy after ischemic stroke is associated with reduced nonfatal vascular events, though mortality benefits may be confounded by frailty.
May warrant adherence support after ischemic stroke; leaves open causality and mortality effects due to confounding.
Adherence to AH agents is associated with adherence to other secondary preventive therapies and a risk reduction for nonfatal vascular events after an ischemic stroke. Overestimation of all-cause mortality reduction may be related to frailty and comorbidities, which may confound the apparent benefit of different drugs.
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Perreault et al. (2012) studied this question.
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