Why the study?
Does parecoxib sodium pretreatment combined with dexmedetomidine reduce the incidence of early postoperative cognitive dysfunction in elderly patients after shoulder arthroscopy?
Does parecoxib sodium pretreatment combined with dexmedetomidine reduce the incidence of early postoperative cognitive dysfunction in elderly patients after shoulder arthroscopy?
Parecoxib sodium combined with dexmedetomidine may reduce early postoperative cognitive dysfunction in elderly patients undergoing shoulder arthroscopy.
Answers are grounded in this paper and cite their sources.
Supports combined parecoxib-dexmedetomidine pretreatment to lower early POCD in elderly patients; extends RCT evidence for multimodal perioperative neuroprotection.
Parecoxib sodium pretreatment combined with dexmedetomidine could reduce the incidence of early postoperative cognitive dysfunction in elderly patients. This might be related to the improvement of postoperative analgesia effect and cerebral oxygen metabolism in patients.
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Lü et al. (2017) studied this question.
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