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February 1, 2019Psoriasis Targets and TherapyOpen Access

Increased dermal expression of chromatin-associated protein HMGB1 and concomitant T-cell expression of the DNA RAGE in patients with psoriasis vulgaris

Lisa Strohbuecker Hans J. P. M. Koenen Esther van Rijssen Bram van Cranenbroek Esther Fasse Irma Joosten Andreas Körber Christoph Bergmann

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Abstract

The presence of HMGB1 and RAGE signaling may impact orchestration of chronic inflammation in PV which might have implications for Treg and Th17 cells.

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Strohbuecker et al. (2019) studied this question.

synapsesocial.com/papers/69dd621f0644c7b49d40d561 https://doi.org/10.2147/ptt.s190507

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