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September 1, 2004Haemophilia43 citations

Clinical manifestations and management of labor and delivery in women with factor IX deficiency*

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MYM. Y. YangMRMargaret V. Ragni

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Abstract

Haemophilia is uncommon in females and little is known about the clinical manifestations and postpartum management of women with this disorder. Clinical characteristics of postpartum bleeding were evaluated in women with factor IX deficiency (FIX:C 0.05 U mL(-1) vs. < or =0.05 U mL(-1)). Compared with females with von Willebrand disease or FXI deficiency, females with FIX deficiency were more likely to experience postpartum bleeding (P = 0.008) and anaemia (P = 0.045); and they were less likely to experience menorrhagia (P = 0.065), but the latter did not reach significance. Postpartum bleeding is common in women with haemophilia B or carriers of haemophilia B, and treatment with factor replacement for at least 4 days of postpartum may prevent bleeding following delivery in such women.

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Yang et al. (2004) studied this question.

synapsesocial.com/papers/69dd627b0644c7b49d40d59ehttps://doi.org/10.1111/j.1365-2516.2004.00946.x
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