Why the study?
Does body mass index affect global brain volume in middle-aged adults?
Does body mass index affect global brain volume in middle-aged adults?
Obesity in middle age is associated with greater brain atrophy, potentially increasing the risk for future cognitive decline.
Supports midlife obesity-atrophy link but cross-sectional data leave causality and intervention effects open.
These findings suggest that middle-aged obese adults may already be experiencing differentially greater brain atrophy, and may potentially be at greater risk for future cognitive decline.
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Ward et al. (2005) studied this question.
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