Blood tau‐PT217 contributes to the anesthesia/surgery‐induced delirium‐like behavior in aged mice

Jing Lu; Feng Liang; Ping Bai; Chenghao Liu; Miao Xu; Zhengwang Sun; Wenjie Tian; Yuanlin Dong; Yiying Zhang; Qimin Quan; Ashok Khatri; Yuan Shen; Edward R. Marcantonio; Gregory Crosby; Deborah J. Culley; Changning Wang; Guang Yang; Zhongcong Xie

doi:10.1002/alz.13118

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Acute increases in blood tau-PT217 may contribute to brain dysfunction and postoperative delirium. Targeting B cells or mitochondrial function may have therapeutic potential for preventing or treating these conditions.

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Lu et al. (2023) studied this question.

synapsesocial.com/papers/69dd66ff80eea7d3f699c81d https://doi.org/10.1002/alz.13118

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Blood tau‐PT217 contributes to the anesthesia/surgery‐induced delirium‐like behavior in aged mice

Abstract

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Blood tau‐PT217 contributes to the anesthesia/surgery‐induced delirium‐like behavior in aged mice

Abstract

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