Why the study?
Do surgery and chemotherapy improve survival in osteosarcoma patients with lung metastasis?
Do surgery and chemotherapy improve survival in osteosarcoma patients with lung metastasis?
In osteosarcoma patients, advanced age and large tumors increase the risk of lung metastasis, and survival in metastatic patients is improved by surgery and chemotherapy but not radiotherapy.
May support surgery plus chemotherapy for lung-metastatic osteosarcoma survival; leaves open causality and radiotherapy effects pending prospective trials.
Advanced age (older than 30 years) and large tumors were related to a higher risk of lung metastases in osteosarcoma patients. Therefore, patients who were diagnosed at advanced age or had large tumors should receive comprehensive chest CT scans. Surgery and chemotherapy can significantly improve the survival of metastatic patients, while radiotherapy did not improve survival in these patients.
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Huang et al. (2019) studied this question.
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