Why the study?
Do cardiac DTI parameters differ between systole and diastole in volunteers?
Do cardiac DTI parameters differ between systole and diastole in volunteers?
Cardiac DTI parameters, including fractional anisotropy, helical angle, and mean diffusivity, vary significantly between systole and diastole, highlighting the importance of cardiac phase in DTI assessment.
Cardiac DTI requires phase-specific norms; hypothesis-generating for standardization before clinical adoption.
Results Two of the original 46 volunteers were excluded due to ECG irregularities. Data from one further volunteer was incomplete and therefore excluded from the final analysis. Results from the remaining 43 volunteers are in table 1. Global FA was higher in diastole than systole (0.56 v 0.47; p < 0.001). The global endocardial HA was significantly more right-handed in systole than diastole (34° v 25°; p < 0.001). The global mesocardial HA was circumferentially orientated and similar in both diastole and systole (-3° v -2°; p = 0.42). The global epicardial HA was slightly more left-handed in systole than diastole (-35° v -30°; p < 0.001). Global MD was higher in diastole than systole (1.11 v 0.93 × 10mm/s; p < 0.001).
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McGill et al. (2014) studied this question.
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