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April 14, 2026Journal of Cerebrovascular SciencesOpen Access

Hypertrophied Atrophy: Two Patient Case Report of Post-stroke Post-gamma Knife Radiosurgery Hypertrophic Olivary Degeneration

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Authors

ARAkshay RajputMTManjul TripathiCAChirag Kamal Ahuja

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Overview

Case report reveals hypertrophic olivary degeneration in patients post-treatment, suggesting careful monitoring is needed.

Key Points

  • To explore the occurrence of hypertrophic olivary degeneration following different types of brain lesions.
  • Case reports of two patients presenting with rubral tremors.
  • Radiological exams using T2/FLAIR MRI to assess olivary nucleus changes.
  • Review of aetiologies including pontine bleed and gamma knife radiosurgery.
  • Both patients exhibited hyperintense signals in the olivary nucleus on MRI.
  • Both cases had a delayed onset of rubral tremor associated with different underlying conditions.
  • The second case is the first reported instance of HOD resulting from gamma knife radiosurgery.

Cite This Study

Rajput et al. (2025) studied this question.

synapsesocial.com/papers/69ddd959e195c95cdefd6ad7https://doi.org/10.4103/jcvs.jcvs_22_25
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Hypertrophic Olivary Degeneration Following Brainstem Hemorrhage in a Patient with Tremor: A Case Report with Serial MRI Follow-Up2026
  2. 2Hypertrophic olivary degeneration following head injury: a case report2024 · 2 citations
  3. 3Hypertrophic olivary degeneration mimicking tumor recurrence after brainstem radiosurgery: A diagnostic pitfall in neuro-oncology2026
  4. 4Hypertrophic olivary degeneration secondary to a Guillain Mollaret triangle cavernoma: Two case report2024 · 1 citations
  5. 5When Degeneration Masquerades as Disease: Diagnosing Hypertrophic Olivary Degeneration on a Single Magnetic Resonance Imaging Examination in an Elderly Patient with Posterior Fossa Hemorrhage2026