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September 1, 1965Proceedings of the National Academy of SciencesOpen Access

The inhibition of vaccinia virus multiplication by isatin-beta-thiosemicarbazone.

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Population

vaccinia virus

Design

Preclinical

Authors

BWBruce WoodsonUniversity of Pittsburgh WJWolfgang K. JoklikHarris–Stowe State University

Discussion

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Member takes

Implication

No clinical implications for poxvirus infections; leaves open translation from animal models.

Structured PICO

P

Population

vaccinia virus

I

Intervention

isatin-beta-thiosemicarbazone

O

Outcome

inhibition of multiplication

Isatin-beta-thiosemicarbazone inhibits vaccinia virus multiplication.

Cite This Study

Woodson et al. (1965) studied this question.

synapsesocial.com/papers/69de4ec27ed287395e558690 https://doi.org/10.1073/pnas.54.3.946

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Also Consider

Synapse has enriched 2 closely related papers on similar clinical questions. Consider them for comparative context:

1Effect of Aliphatic Oxime and Isatin Thiosemicarbazones on Vaccinia Infection in the Mouse and in the Rabbit1953 · 51 citations
2Biochemical Effects of Isatin -Thiosemicarbazone on Development of Vaccinia Virus1962 · 23 citations