What question did this study set out to answer?

To evaluate the efficacy, safety, and hemodynamic impact of riociguat in patients diagnosed with pulmonary hypertension secondary to systolic left ventricular dysfunction.

June 17, 2013Circulation

Riociguat for Patients With Pulmonary Hypertension Caused by Systolic Left Ventricular Dysfunction

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To evaluate the efficacy, safety, and hemodynamic impact of riociguat in patients diagnosed with pulmonary hypertension secondary to systolic left ventricular dysfunction.
Interventional randomized trial registered with ClinicalTrials.gov identifier NCT01065454.
Investigates the pharmacological effect of riociguat in patients with pulmonary hypertension secondary to systolic left ventricular dysfunction.
Clinical trial registration entry (NCT01065454) lists no numerical event rates, effect sizes, or confidence intervals for the primary outcome.
Investigation qualitative focus addresses hemodynamic adjustments and clinical tolerability associated with riociguat treatment.

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Implication

Randomized trial reports evaluation of riociguat in pulmonary hypertension with systolic left ventricular dysfunction, indicating therapeutic investigation in heart failure.

Cite This Study

Bonderman et al. (2013) studied this question.

synapsesocial.com/papers/69de4fabbf539e22705584e7 https://doi.org/10.1161/circulationaha.113.001458

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Implication

Randomized trial reports evaluation of riociguat in pulmonary hypertension with systolic left ventricular dysfunction, indicating therapeutic investigation in heart failure.

Riociguat for Patients With Pulmonary Hypertension Caused by Systolic Left Ventricular Dysfunction

Key Points

No abstract yet

Discussion

Implication

Cite This Study

Riociguat for Patients With Pulmonary Hypertension Caused by Systolic Left Ventricular Dysfunction

Key Points

No abstract yet

Discussion

Implication

Cite This Study

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